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Biomarkers to discriminate between aseptic loosened and stable total hip or knee arthroplasties: a systematic review.

Shaho HasanPeter van SchieBart L KapteinJan W SchoonesPerla J Marang-van de MheenRob R G H H Nelissen
Published in: EFORT open reviews (2024)
Several serum and urine markers were promising in discriminating between loosened and stable implants. We recommend future studies to evaluate these biomarkers in a longitudinal fashion to assess whether progression of loosening is associated with a change in these biomarkers. In particular, high-quality studies assessing the usability of these biomarkers are needed.
Keyphrases
  • total hip
  • total knee arthroplasty
  • case control