Euglycemic Diabetic Ketoacidosis in the ICU: 3 Case Reports and Review of Literature.
Pablo LuceroSebastián Pablo ChapelaPublished in: Case reports in critical care (2018)
Diabetic ketoacidosis (DKA) is an acute complication of diabetes mellitus, both type I and type II, as well as other types with diabetes such gestacional diabetes mellitus. It is characterized by blood glucose levels greater than 250 mg/dL and metabolic acidosis (pH < 7.3 and serum bicarbonate < 15 mEq/dL) with an increased anion gap and the presence of ketone bodies in the blood or urine. Within this pathology, there is a subgroup of pathologies which are characterized by being present with no signs of hyperglycemia, posing a diagnostic challenge due to the absence of the main sign of the pathology and the diversity of their pathophysiology. In this article, we will present 3 clinical cases with 3 different forms of clinical presentation: a case of DKA in pregnancy, a case of DKA associated with the use of sodium-glucose cotransporter 2 (SGLT-2) inhibitors, and a third case related to sepsis, together with a narrative review of the literature on the topic.
Keyphrases
- glycemic control
- blood glucose
- type diabetes
- intensive care unit
- liver failure
- wound healing
- weight loss
- insulin resistance
- cardiovascular disease
- respiratory failure
- drug induced
- case report
- preterm birth
- acute kidney injury
- mechanical ventilation
- ionic liquid
- septic shock
- clinical trial
- pregnancy outcomes
- metabolic syndrome
- phase iii
- extracorporeal membrane oxygenation