Enhancing Cervical Cancer Prevention in South African Women: Primary HPV mRNA Screening with Different Genotype Combinations.

Sveinung Wergeland SørbyeBente Marie FalangMatthys H BothaLeon Cornelius SnymanHaynes van der Merwe Cathy VisserKarin RichterGreta Dreyer

Published in: Cancers (2023)

Employing mRNA HPV tests within a test-and-treat approach holds huge promise for targeted cervical cancer prevention in under-screened populations. Testing for mRNA of the 6 highest-risk HPV types in this population and treating them all is projected to effectively prevent progression from CIN3 to invasive cervical cancer while reducing overtreatment in resource-constrained settings.

Keyphrases

cervical cancer screening
high grade
binding protein
polycystic ovary syndrome
climate change
type diabetes
big data
adipose tissue
insulin resistance