Measuring Visceral Adipose Tissue Metabolic Activity in Sleep Apnea Utilizing Hybrid 18F-FDG PET/MRI: A Pilot Study.
Vaishnavi KundelDaniel LehaneSarayu RamachandranZahi FayadPhilip RobsonNeomi ShahVenkatesh ManiPublished in: Nature and science of sleep (2021)
Derangements in VAT metabolic activity are implicated in adverse cardiometabolic outcomes and may be one of the key drivers of CV risk in OSA. Our results are hypothesis-generating, and suggest that VAT should be investigated in future studies using multi-modal imaging to understand its role as a potential mediator of adverse cardiometabolic risk in OSA.
Keyphrases
- sleep apnea
- obstructive sleep apnea
- positive airway pressure
- adipose tissue
- pet ct
- insulin resistance
- positron emission tomography
- pet imaging
- computed tomography
- magnetic resonance imaging
- high resolution
- contrast enhanced
- magnetic resonance
- high fat diet
- photodynamic therapy
- weight loss
- single molecule
- breast cancer risk