Association between long interspersed nuclear element-1 methylation levels and relapse in Wilms tumors.

Bruna M de Sá PereiraRafaela Montalvão-de-AzevedoPaulo Antônio FariaNeimar de Paula SilvaPedro Nicolau-NetoMariana MaschiettoBeatriz de CamargoSheila Coelho Soares Lima

Published in: Clinical epigenetics (2017)

Our results reinforce previous data showing a global hypomethylation profile in WT. LINE-1 methylation levels can be suggested as a marker of relapse after chemotherapy treatment in addition to risk classification, helping to guide new treatment approaches.

Keyphrases

dna methylation
genome wide
machine learning
deep learning
squamous cell carcinoma
big data
electronic health record
smoking cessation