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Quantitative susceptibility mapping evaluation of glioma.

Shanmei ZengHui MaDingxiang XieYingqian HuangMengzhu WangWenting ZengNengjin ZhuZuliwei MaZhiyun YangJianping ChuJing Zhao
Published in: European radiology (2023)
• Morphologically, gliomas with a heterogeneous intratumoural susceptibility signal (ITSS) are more similar to high-grade gliomas (p = 0.006; AUC, 0.72; sensitivity, 70%; and specificity, 73%). Heterogeneous ITSS was significantly associated with tumour haemorrhage, necrosis, diffusion restriction, and avid enhancement but did not change between pre- and post-enhanced QSM. • Tumour parenchyma's relatively low magnetic susceptibility helped identify oligodendroglioma with high specificity. • Tumour parenchyma magnetic susceptibility was significantly correlated with ADC (r = 0.61) and Cho/NAA (r = 0.40).
Keyphrases
  • high grade
  • low grade
  • magnetic resonance
  • structural basis
  • diffusion weighted