Porphyromonas gingivalis promotes the progression of oral squamous cell carcinoma by stimulating the release of neutrophil extracellular traps in the tumor immune microenvironment.

Zhi-Chen GuoSi-Li JingXin-Yu JiaSadam Ahmed ElayahLin-Yang XieHao CuiJun-Bo Tu Si-Jia Na

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2023)

High expression of NETs-related markers demonstrates a strong correlation with the progression of OSCC. Inhibition of the NETs release process stimulated by P. gingivalis and targeted NETs could potentially open up a novel avenue in the field of immunotherapy for patients afflicted with OSCC.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
stem cells
prognostic factors
minimally invasive
peritoneal dialysis
patient reported outcomes
drug delivery