Safety of Technique and Procedure of Stromal Vascular Fraction Therapy: From Liposuction to Cell Administration.
Karina KarinaIis RoslianaImam RosadiRachel SchwartzSiti SobariahIrsyah AfiniTias WidyastutiMelinda RemeliaKomang Ardi WahyuningsihJeanne Adiwinata PawitanPublished in: Scientifica (2020)
Our results showed that administration of high dose of SVF until 10 billion cells in a majority of 421 patients through infusion, spinal, and intra-articular injection was feasible without causing major adverse events and should be further investigated in well-designed phase I-II clinical trial to address the safety and efficacy of therapy.
Keyphrases
- high dose
- clinical trial
- end stage renal disease
- low dose
- induced apoptosis
- ejection fraction
- newly diagnosed
- cell therapy
- bone marrow
- peritoneal dialysis
- prognostic factors
- single cell
- spinal cord
- stem cells
- minimally invasive
- stem cell transplantation
- open label
- patient reported outcomes
- spinal cord injury
- endoplasmic reticulum stress