Effect of functional variant rs11466313 on breast cancer susceptibility and TGFB1 promoter activity.

Yan-Ting ZhouLi-Yuan ZhengYa-Jun WangLi YangYun-Tao XieIpsita PandaXin-Xia TianWei-Gang Fang

Published in: Breast cancer research and treatment (2020)

This study elucidates the impact of functional polymorphism rs11466313 in the regulatory region of TGFB1 on breast cancer susceptibility and gene expression, and could be helpful for future research to determine the value of this TGFB1 variant in the clinical setting.

Keyphrases

gene expression
dna methylation
transcription factor
current status
breast cancer risk