Multiomics profiling reveals the benefits of gamma-delta (γδ) T lymphocytes for improving the tumor microenvironment, immunotherapy efficacy and prognosis in cervical cancer.
Junyi LiYuanjie CaoYancheng LiuLu YuZhen ZhangXiaofeng WangHui BaiYuhan ZhangShaochuan LiuMiaomiao GaoChenglu LuChen LiYong GuanZhen TaoZhiqiang WuJie ChenZhi-Yong YuanPublished in: Journal for immunotherapy of cancer (2024)
γδ T cells play a beneficial role in antitumor immunity in cervical cancer. The abundance of γδ T cells in cervical cancerous tissue is associated with higher response rates to immunotherapy.
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