Improving clinical utility of GAD65 autoantibodies by electrochemiluminescence assay and clinical phenotype when identifying autoimmune adult-onset diabetes.
Yong GuXiaofan JiaTanwi VartakDongmei MiaoFran DongSamuel T JerramMarian RewersAssiamira FerraraJean M LawrenceLiping YuRichard David Leslienull nullPublished in: Diabetologia (2021)
Detection of GADA by ECL assay, given technical advantages over RBA-GADA, identified adult-onset diabetes patients at higher risk of requiring early insulin treatment, as did clinical phenotype, together allowing for more accurate clinical diagnosis and management.