Modernizing Clinical Trial Eligibility Criteria: Recommendations of the ASCO-Friends of Cancer Research Washout Period and Concomitant Medication Work Group.
Robert Donald HarveyKathryn F MilehamVishal BhatnagarJamie R BrewerAtiqur RahmanCassadie MoravekAndrew S KennedyElizabeth A NessE Claire DeesS Percy IvyScot W EbbinghausCaroline SchenkelThomas S UldrickPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Arbitrary or blanket washout and concomitant medication exclusions should be eliminated. Where there is evidence to support them, clinically relevant washout periods and concomitant medication-related eligibility criteria may be included.See related commentary by Giantonio, p. 2369.