Morphometric analysis program: Detection of epileptic foci in young children using an adult normative database: Initial experience.
Ximena StecherValeria SchonstedtCarla ManterolaFernando CarreñoFrancisco ZamoranoAlvaro VelasquezMauricio CastilloPublished in: Epilepsia open (2021)
FCD is the most frequent pathology reported in pediatric epilepsy surgery series (Epileptic Disord, 18, 2016, 240). Significant number of FCDs may be overlooked on MRIs, reducing the odds of seizure freedom after surgery (Epilepsy Res, 89, 2010, 310). MAP is an image postprocessing method for enhanced visualization of FCD; however, when using an adult template in developing brains, normal subcortical regions may be highlighted as pathological. Creating a pediatric template is difficult, due to the need for general anesthesia to acquire the MRI database. Here, we were able to show that MAP identified FCDs as asymmetric "U-" shaped highlighted regions in the junction maps of all five patients, which may indicate that obtaining childhood databases for this purpose may not be necessary and that adult ones suffice for diagnosis of FCD.
Keyphrases
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- childhood cancer
- minimally invasive
- peritoneal dialysis
- magnetic resonance imaging
- prognostic factors
- emergency department
- deep learning
- adverse drug
- coronary artery bypass
- quality improvement
- patient reported outcomes
- contrast enhanced
- high density
- magnetic resonance
- mass spectrometry
- big data
- patient reported
- surgical site infection
- diffusion weighted imaging
- solid state