Immune checkpoint inhibitor therapy and outcomes from SARS-CoV-2 infection in patients with cancer: a joint analysis of OnCovid and ESMO-CoCARE registries.
Alessio CortelliniGino M DettorreUrania DafniJuan Aguilar-CompanyLuis Castelo-BrancoMatteo LambertiniSpyridon GennatasVasileios AngelisAilsa Sita-LumsdenJacobo RogadoPaolo PedrazzoliDavid ViñalAleix PratMaura RossiRossana BerardiTeresa Alonso-GordoaSalvatore GrisantiGeorgia DimopoulouPaola QueiroloSylvain PradervandAlexia BertuzziMark BowerDirk ArnoldRamón SalazarMarco TucciKevin J HarringtonFrancesca MazzoniUma MukherjeeZoi TsourtiOlivier MichielinFanny PommeretJoan BrunetBruno VincenziGiuseppe ToniniAndrea PatriarcaFederica BielloMarco KrengliJosep TaberneroGeorge PentheroudakisAlessandra GennariSolange PetersEmanuela RomanoDavid James PinatoPublished in: Journal for immunotherapy of cancer (2022)
Anti-SARS-CoV-2 vaccination reduces morbidity and mortality from COVID-19 in ICI recipients. History of irAEs might identify patients with pre-existing protection from COVID-19, warranting further investigation of adaptive immune determinants of protection from SARS-CoV-2.