Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical circulatory support.
Yann MarquetGuillaume HékimianGuillaume LebretonMathieu KerneisPhilippe RouvierPierre BayAlexis MathianNicolas BréchotJuliette ChommelouxMatthieu PetitMelchior GautierLucie LefevreOuriel SauraDavid LevyPaul QuentricQuentin MoyonSofia OrtunoMatthieu SchmidtPascal LeprinceCharles-Edouard LuytAlain CombesMarc Pineton de ChambrunPublished in: Annals of intensive care (2023)
In clinically suspected myocarditis unweanable from MCS, myocardial biopsy increased the rate of definite myocarditis but was associated with a low rate of treatment modification and a significant proportion of adverse events. We believe the benefit/risk ratio of myocardial biopsy should be more carefully weighted in these frail and selected patients than suggested by actual guidelines. Further prospective studies are now needed to determine its value in patients under MCS.