Laminar analysis of the cerebellar cortex shows widespread damage in early MS patients: A pilot study at 7T MRI.

Riccardo GalbuseraKatrin ParmarYohan BoillatMario Joao FartariaAlexandra-Ramona TodeaKieran O' BrienAnna SmolinskiLudwig KapposWietske van der ZwaagCristina Granziera

Published in: Multiple sclerosis journal - experimental, translational and clinical (2020)

We found MRI evidence of damage in the normal-appearing cerebellar cortex at early MS stages and before volumetric changes. This microstructural alteration appears to be related to EDSS and cognitive performance.

Keyphrases

end stage renal disease
mass spectrometry
multiple sclerosis
magnetic resonance imaging
contrast enhanced
ms ms
oxidative stress
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
peritoneal dialysis
computed tomography
magnetic resonance
white matter