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Non-invasive detection of orthotopic human lung tumors by microRNA expression profiling of mouse exhaled breath condensates and exhaled extracellular vesicles.

Megan I MitchellIddo Z Ben-DovChristina LiuTao WangRachel B HazanThomas L BauerJohannes ZakrzewskiKathryn DonnellyKar ChowJunfeng MaOlivier Loudig
Published in: Extracellular vesicles and circulating nucleic acids (2024)
This study is the first of its kind and demonstrates that lung tumor EVs are exhaled in mice and provide non-invasive biomarkers for detection of lung tumors.
Keyphrases
  • loop mediated isothermal amplification
  • real time pcr
  • label free
  • genome wide
  • gene expression
  • high fat diet induced
  • dna methylation
  • adipose tissue
  • skeletal muscle
  • quantum dots
  • wild type