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Retrosynthetic Simplicity.

Mark D Levin
Published in: Synlett : accounts and rapid communications in synthetic organic chemistry (2023)
Retrosynthetic simplicity is introduced as a metric by which methods can be evaluated. An argument in favor of reactions which are retrosynthetically simple is put forward, and recent examples in the context of skeletal editing from my own laboratory as well as contributions from others are analyzed critically through this lens.
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