The methylation level of a single cancer risk marker gene reflects methylation burden in gastric mucosa.

Takahiro IrieHarumi YamadaChihiro TakeuchiYu-Yu LiuHadrien CharvatTaichi ShimazuTakayuki AndoTakao MaekitaSeiichiro AbeHiroyuki TakamaruMasaaki KodamaKazunari MurakamiKiichi SugimotoKazuhiro SakamotoToshikazu Ushijima

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2023)

The methylation level of a single marker gene reflects the methylation burden, which includes driver gene methylation, and thus accurately predicts cancer risk.

Keyphrases

genome wide
dna methylation
copy number
genome wide identification
gene expression
risk factors