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Curcumin potentiates the anti-inflammatory effects of Tehranolide by modulating the STAT3/NF-κB signaling pathway in breast and ovarian cancer cell lines.

Havva AfshariShokoofe NooriAfshin Zarghi
Published in: Inflammopharmacology (2023)
This investigation indicated for the first time that Tehranolide, either alone or in combination with curcumin, exerted its anti-inflammatory effects by suppressing NF-κB and STAT3 signaling pathways in SKOV3 and MDA-MB-231 cells.
Keyphrases
  • signaling pathway
  • induced apoptosis
  • pi k akt
  • cell cycle arrest
  • cell proliferation
  • epithelial mesenchymal transition
  • breast cancer cells
  • cell death
  • oxidative stress
  • lps induced
  • inflammatory response