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Fibroblast growth factor 10 attenuates chronic obstructive pulmonary disease by protecting against glycocalyx impairment and endothelial apoptosis.

Mingxiang FengWeiping HuShaoyuan ZhangChanghao RenSiyun LinZhenyu ZhouHao WuJun YinLijie Tan
Published in: Respiratory research (2022)
Our results suggest that FGF10 may serve as a potential therapeutic strategy against COPD via endothelial repair and glycocalyx reconstitution.
Keyphrases
  • chronic obstructive pulmonary disease
  • lung function
  • endothelial cells
  • oxidative stress
  • endoplasmic reticulum stress
  • cell death
  • cell cycle arrest
  • signaling pathway