Micelle-Incorporated Liquid Chromatography in the Light of Green Chemistry: An Application for the Quality Control Analysis of Anti-Platelet Fixed-Dose Combinations.
Ahmed ElsonbatyWafaa S HassanMaya S EissaSara AbdulwahabPublished in: Journal of AOAC International (2022)
The developed method was successfully applied for the determination of clopidogrel bisulfate (CPS), aspirin (ASP), together with salicylic acid (SA), in their pharmaceutical dosage form.
Keyphrases
- quality control
- liquid chromatography
- antiplatelet therapy
- solid phase extraction
- mass spectrometry
- acute coronary syndrome
- high resolution mass spectrometry
- tandem mass spectrometry
- low dose
- percutaneous coronary intervention
- molecularly imprinted
- cardiovascular events
- simultaneous determination
- drug discovery
- cardiovascular disease
- high resolution
- type diabetes
- atrial fibrillation