IL-23 regulates inflammatory osteoclastogenesis via the activation of MDL-1 + osteoclast precursors.

Hiroki Furuya Cuong Thach NguyenRan GuShie-Liang HsiehEmanual MaverakisIannis E Adamopoulos

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2023)

Our data show that IL-23 signaling regulates the availability of osteoclast precursors in inflammatory arthritis that could be effectively targeted for the treatment of inflammatory bone loss in inflammatory arthritis.

Keyphrases

bone loss
oxidative stress
rheumatoid arthritis
cancer therapy
big data
drug delivery
artificial intelligence