Phenotyping of COPD with MRI in comparison to same-day CT in a multi-centre trial.
Sebastian NauckMoritz PohlBertram J JobstClaudius MelzigHagen MeredigOliver WeinheimerSimon TriphanOyunbileg von StackelbergPhilip KonietzkeHans-Ulrich KauczorClaus P HeußelMark O WielpützJürgen Biederernull nullPublished in: European radiology (2024)
• In a multi-centre setting, MRI and CT showed substantial concordance for phenotyping of COPD (airway-/emphysema-/mixed-type). • Individual features of COPD demonstrated variable inter-modality concordance with features of pulmonary hypertension showing the highest and bronchiectasis showing the lowest concordance. • For all single features of COPD, inter-reader agreement was lower on MRI than on CT.
Keyphrases
- contrast enhanced
- chronic obstructive pulmonary disease
- lung function
- magnetic resonance imaging
- computed tomography
- magnetic resonance
- image quality
- pulmonary hypertension
- cystic fibrosis
- dual energy
- diffusion weighted imaging
- high throughput
- air pollution
- clinical trial
- coronary artery
- pulmonary artery
- study protocol
- phase ii
- phase iii
- open label
- pulmonary fibrosis
- double blind