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Growth differentiation factor 15 (GDF15) and semaglutide inhibit food intake and body weight through largely distinct, additive mechanisms.

M GhidewonH S WaldA D McKnightBart C De JongheD M BreenA L AlhadeffTito BornerH J Grill
Published in: Diabetes, obesity & metabolism (2022)
GDF15 and semaglutide reduce food intake and body weight through largely distinct processes that produce greater weight loss and feeding suppression when combined.
Keyphrases
  • body weight
  • weight loss
  • bariatric surgery
  • roux en y gastric bypass
  • metabolic syndrome
  • skeletal muscle