Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort.
Yik Weng YewTheresia MinaHong Kiat NgBenjamin Chih Chiang LamElio RiboliEng Sing LeeJimmy LeeJoanne Ngeow Yuen YiePaul ElliottSteven Tien Guan ThngJohn C ChambersMarie LohPublished in: International journal of obesity (2005) (2023)
We establish strong association of BMI with TEWL and skin pH, with MR results suggestive of a possible causal relationship of obesity with TEWL. It emphasizes the potential impact of obesity on skin barrier function and therefore opportunity for primary prevention.