MR1: An unconventional twist in the tail.

Published in: The Journal of cell biology (2022)

MR1 is a conserved molecule that binds microbial vitamin B metabolites and presents them to unconventional T cells. Lim and colleagues (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202110125) uncover the role of AP2 in ensuring MR1 surface presentation, which relies on an atypical motif within the MR1 cytoplasmic tail.

Keyphrases

contrast enhanced
magnetic resonance
transcription factor
single cell
magnetic resonance imaging
microbial community
ms ms
epithelial mesenchymal transition
stem cells
computed tomography
signaling pathway