Hyperglycaemia-associated Caspase-3 predicts diabetes and coronary artery disease events.
Jiangming SunPratibha SinghJohan ÖsterlundMarju Orho-MelanderOlle MelanderGunnar EngströmAndreas EdsfeldtPublished in: Journal of internal medicine (2021)
The present study provides evidence for plasma sCaspase-3 as a marker of cardio-metabolic risk factors and as a predictor of future diabetes and CAD in a cohort without cardiovascular disease or diabetes at baseline.
Keyphrases
- cardiovascular disease
- type diabetes
- coronary artery disease
- risk factors
- glycemic control
- cardiovascular events
- cell death
- percutaneous coronary intervention
- heart failure
- cardiovascular risk factors
- current status
- insulin resistance
- adipose tissue
- skeletal muscle
- induced apoptosis
- transcatheter aortic valve replacement
- endoplasmic reticulum stress
- weight loss