Validation of simplified uptake measures against dynamic Patlak K i for quantification of lesional 89 Zr-Immuno-PET antibody uptake.
Jessica E WijngaardenMarc C HuismanYvonne W S JauwGuus A M S van DongenHenri N J M GreuterRobert C SchuitMatthew ClevelandElske C GootjesDaniëlle J VugtsC Willemien Menke-van der Houven van OordtRonald BoellaardPublished in: European journal of nuclear medicine and molecular imaging (2023)
Zr-Immuno-PET uptake when constant mass doses were administered. However, for variable mass doses, only TPR and TBR provided reliable values for irreversible uptake, but not SUV, because SUV does not take patient and mass dose-specific plasma clearance into account.