Association between clinical dementia rating and clinical outcomes in Alzheimer's disease.
Krista L LanctôtMercè BoadaPierre N TariotFiras DabbousJulie Hahn-PedersenSariya UdayachalermLars Lau RaketCynthia Saiontz-MartinezWojciech MichalakWendy WeidnerJeffrey CummingsPublished in: Alzheimer's & dementia (Amsterdam, Netherlands) (2024)
There were strong associations among CDR and the various outcomes relevant to healthcare providers, patients, and their care givers, such as activities of daily living.Overall, activities of daily living, neuropsychiatric symptoms, and cognitive function outcomes deteriorated over time and can be observed in early stages of AD (MCI or mild dementia).Our findings directly inform the current understanding of AD progression and can aid in care planning and benefit assessments of early AD interventions to delay the progression of AD to more advanced stages.
Keyphrases
- healthcare
- mild cognitive impairment
- end stage renal disease
- palliative care
- cognitive decline
- ejection fraction
- cognitive impairment
- newly diagnosed
- chronic kidney disease
- quality improvement
- physical activity
- prognostic factors
- peritoneal dialysis
- metabolic syndrome
- patient reported outcomes
- insulin resistance
- depressive symptoms
- skeletal muscle
- chronic pain