Dispersion-induced cooperative hydrogen atom transfer for radical iodoalkylation.

Described herein is a novel visible-light-promoted three-component radical iodo-alkylative cyclization of alkynes using iodoform as a bifunctional iodine atom source. Visible-light irradiation of a polar-polar interaction complex of iodoform with malonate enables the cooperative hydrogen atom transfer process to generate alkyl radical and trigger a cascade reaction sequence.