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An anchored simulated treatment comparison of uptitration of amlodipine compared with a low-dose combination treatment with amlodipine 5 mg/bisoprolol 5 mg for patients with hypertension suboptimally controlled by amlodipine 5 mg monotherapy.

Caroline FochJan FeifelUlrike Hostalek-Gottwald
Published in: Current medical research and opinion (2022)
In this indirect comparison, a more important decrease was observed in DBP with the low-dose combination as compared to the alternative therapeutic approach of up-titration from amlodipine 5 mg to amlodipine 10 mg. No meaningful difference was seen for SBP.
Keyphrases
  • low dose
  • hypertensive patients
  • blood pressure
  • high dose
  • combination therapy
  • clinical trial