Albumin determined by bromocresol green leads to erroneous results in routine evaluation of patients with chronic kidney disease.
Marith van Schrojenstein LantmanAnne-Els van de LogtElma Prudon-RosmulderMarloes LangelaanAyşe Y DemirSteef KurstjensArmando van der HorstAldy KuypersAram GreuterJenny E Kootstra-RosEline van der HagenMarlies OostendorpRoseri de BeerChristian RamakersDirk BakkerenFokke LindeboomDennis van de WijngaartMarc H M ThelenJack WetzelsMiranda van BerkelPublished in: Clinical chemistry and laboratory medicine (2023)
Our study shows that BCP is fit for the intended use to measure plasma albumin levels in CKD patients from all stages, including patients on hemodialysis. In contrast, most BCG-based platforms falsely overestimate the plasma albumin concentration.