Chimerism evaluation in measurable residual disease-suspected cells isolated by flow cell sorting as a reliable tool for measurable residual disease verification in acute leukemia patients after allogeneic hematopoietic stem cell transplantation.
Alexandra SemchenkovaVarvara BrilliantovaLarisa ShelikhovaVladimir ZhogovOlga IllarionovaEkaterina MikhailovaElena RaykinaElena SkorobogatovaGalina NovichkovaAlexey MaschanMichael MaschanAlexander PopovPublished in: Cytometry. Part B, Clinical cytometry (2020)
We believe that a combination of MFC, cell sorting, and chimerism testing may help confirm or disprove MRD presence in complicated cases after HSCT.
Keyphrases
- allogeneic hematopoietic stem cell transplantation
- acute lymphoblastic leukemia
- acute myeloid leukemia
- single cell
- end stage renal disease
- cell therapy
- induced apoptosis
- ejection fraction
- newly diagnosed
- chronic kidney disease
- mesenchymal stem cells
- cell proliferation
- patient reported outcomes
- bone marrow
- cell death
- endoplasmic reticulum stress
- hematopoietic stem cell