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Re-Dosing del Nido cardioplegia in adult cardiac surgery: Perfusion characteristics and outcomes--Is there an optimal redosing strategy?

Alexander P KossarSamantha NemethYaagnik D KosuriBrigitte E KazziEmily HonzelAlex D'AngeloJessica SpellmanKoji TakedaHiroo TakayamaVinayak BapatMichael ArgenzianoJames BeckCraig R SmithPaul KurlanskyIsaac George
Published in: Perfusion (2023)
In this retrospective study, variations in re-dosing strategy for del Nido cardioplegia do not affect postoperative outcomes and increased CPB time is associated with increased operative mortality, myocardial infarction, need for post-operative CSDs, and reduced postoperative EF, and increased VIS, irrespective of the re-dosing strategy. Further studies are warranted to to identify additional patient and operative characteristics that predispose to complications.
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