Combination therapy with immune check point inhibitors and acute kidney injury.

Amalie ValentinAnne Kirstine Hundahl MøllerJesper Andreas PalshofBo BrobergEva GravesenInge Marie Svane Ditte Hansen

Published in: Acta oncologica (Stockholm, Sweden) (2023)

Patients receiving combination therapy with checkpoint inhibitors are at high risk of AKI, but different causes of AKI should always be considered. Use of PPI concurrently with ICIs is likely to increase the risk of AKI.

Keyphrases

combination therapy
acute kidney injury
cardiac surgery
dna damage
cell cycle
protein protein
oxidative stress
small molecule