Mesenchymal stem cells limit vascular and epithelial damage and restore the impermeability of the urothelium in chronic radiation cystitis.

Clément BrossardAnne-Laure PoulietAnne-Charlotte LefrancMohamedamine BenadjaoudMorgane Dos SantosChristelle DemarquayValerie BuardMarc BenderitterJean-Marc SimonFabien MilliatAlain Chapel

Published in: Stem cell research & therapy (2023)

These results are in favor of MSCs acting to limit progression of the chronic phase of radiation cystitis. MSC treatment may afford real hope for all patients suffering from chronic radiation cystitis resistant to conventional treatments.

Keyphrases

mesenchymal stem cells
end stage renal disease
chronic kidney disease
newly diagnosed
umbilical cord
ejection fraction
peritoneal dialysis
prognostic factors
radiation induced
bone marrow
drug induced
radiation therapy
combination therapy
cell therapy