Feasibility of Continuous Infusion of Cefiderocol in Conjunction with the Establishment of Therapeutic Drug Monitoring in Patients with Extensively Drug-Resistant Gram-Negative Bacteria.

Carolin PrinzFrank StreitChristian SchumannAnna DudakovaChristian LanckohrJulie SchanzMatthias BohnUwe GroßKonrad MeissnerOnnen Moerer Lars-Olav Harnisch

Published in: Clinical drug investigation (2023)

(Quasi) continuous application of cefiderocol 6 g/24 h in conjunction with TDM is a feasible mode of application; the sample for TDM should either be immediately analyzed, cooled, or frozen prior to analysis.

Keyphrases

drug resistant
multidrug resistant
gram negative
acinetobacter baumannii
low dose
solid state