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Measuring similarity between gene interaction profiles.

Joëlle Barido-SottaniSamuel D ChapmanEvsey KosmanArcady R Mushegian
Published in: BMC bioinformatics (2019)
The discovery of molecular modules in genetic networks is sensitive to the way of measuring similarity between profiles of gene interactions in a cell. In the absence of a formal way to choose the "best" measure, it is advisable to explore the measures with different mathematical properties, which may identify different sets of connections between genes.
Keyphrases
  • genome wide
  • genome wide identification
  • copy number
  • dna methylation
  • small molecule
  • single cell
  • cell therapy
  • transcription factor
  • stem cells
  • single molecule