Effect of Low-Dose Methotrexate on eGFR and Kidney Adverse Events: A Randomized Clinical Trial.
Jeffrey A SparksKathleen M M VanniMatthew A SparksChang XuLeah M SantacroceRobert J GlynnPaul M RidkerDaniel H SolomonPublished in: Journal of the American Society of Nephrology : JASN (2021)
These results demonstrate the kidney safety of LD-MTX among patients with normal kidney function or mild-to-moderate CKD at baseline.