Onconephrology: The intersections between the kidney and cancer.
Mitchell H RosnerKenar D JhaveriBlaithin A McMahonMark A PerazellaPublished in: CA: a cancer journal for clinicians (2020)
Onconephrology is a new subspecialty of nephrology that recognizes the important intersections of kidney disease with cancer. This intersection takes many forms and includes drug-induced nephrotoxicity, electrolyte disorders, paraneoplastic glomerulonephritis, and the interactions of chronic kidney disease with cancer. Data clearly demonstrate that, when patients with cancer develop acute or chronic kidney disease, outcomes are inferior, and the promise of curative therapeutic regimens is lessened. This highlights the imperative for collaborative care between oncologists and nephrologists in recognizing and treating kidney disease in patients with cancer. In response to this need, specific training programs in onconephrology as well as dedicated onconephrology clinics have appeared. This comprehensive review covers many of the critical topics in onconephrology, with a focus on acute kidney injury, chronic kidney disease, drug-induced nephrotoxicity, kidney disease in stem cell transplantation, and electrolyte disorders in patients with cancer.
Keyphrases
- drug induced
- liver injury
- chronic kidney disease
- papillary thyroid
- stem cell transplantation
- end stage renal disease
- acute kidney injury
- squamous cell
- high dose
- adverse drug
- public health
- primary care
- palliative care
- type diabetes
- liver failure
- insulin resistance
- cardiac surgery
- childhood cancer
- adipose tissue
- rectal cancer
- hepatitis b virus
- glycemic control
- acute respiratory distress syndrome