Diagnostic and prognostic power of CSF Tau in amyotrophic lateral sclerosis.

Antonio Scarafino Eustachio D'Errico Alessandro IntronaAngela FraddosioEugenio DistasoIrene TempestaAntonella MoreaAntonella MastronardiRosaria LeanteMaddalena RuggieriMariangela MastrapasquaIsabella Laura Simone

Published in: Journal of neurology (2018)

CSF t-Tau showed no reliable diagnostic significance but the relation between the high levels of CSF t-Tau and short survival suggests the potential prognostic role of this biomarker in ALS. However, CSF NFL was confirmed to be the most reliable and efficient tool for diagnosis and prediction of clinical progression and survival in ALS patients.

Keyphrases

cerebrospinal fluid
end stage renal disease
ejection fraction
newly diagnosed
amyotrophic lateral sclerosis
prognostic factors
risk assessment
climate change