Synthetic Cooling Agent in Oral Nicotine Pouch Products Marketed as "Flavor-Ban Approved".
Sairam V JabbaHanno C ErythropelJackson G WoodrowPaul T AnastasStephanie S O'MalleySuchitra Krishnan-SarinJulie Beth ZimmermanSven-Eric JordtPublished in: bioRxiv : the preprint server for biology (2023)
Synthetic cooling agents such as WS-3 found in 'Flavor-Ban Approved' Zyn-"Chill" can provide a robust cooling sensation with reduced sensory irritancy, thereby increasing product appeal and use. The label "Flavor-Ban Approved" is misleading and may implicate health benefits. Regulators need to develop effective strategies for the control of odorless sensory additives used by the industry to bypass flavor bans.