[Gender characteristics of anxiety disorders].

Anxiety and depression are an extremely significant issue of the modern society. According to the epidemiological data, the development of various affective syndromes shows gender-related differences. For example, clinically significant anxiety occurs 2.5 times more often in women than in men. Anxiety disorders in women are characterized by less favorable course, a tendency to relapses and chronification, and also by poor clinical response to therapy. Taking gender differences into account, a significant role of reproductive hormones may be assumed in development of both affective disorders and the features of the course of the disease. In this review we discuss various effects of testosterone, estrogens that can influence development risks of anxiety and depression, as well as possibly influence therapeutic choices.