Participation in a Heart Failure Clinical Trial: Perspectives and Opportunities From the VICTORIA Trial and VICTORIA Simultaneous Registry.
Justin A EzekowitzRobert J MentzCynthia M WesterhoutNancy K SweitzerMichael M GivertzIliana L PiñaChristopher M O'ConnorStephen J GreeneCiaran McMullanLothar RoessigAdrian F HernandezPaul W ArmstrongPublished in: Circulation. Heart failure (2021)
Patients with worsening heart failure in routine clinical practice exhibit high-risk features, and approximately one-third were eligible for an RCT but excluded. The majority of these nonparticipating patients had modifiable reasons. Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT02861534.
Keyphrases
- heart failure
- clinical practice
- clinical trial
- end stage renal disease
- study protocol
- ejection fraction
- newly diagnosed
- chronic kidney disease
- phase ii
- phase iii
- left ventricular
- peritoneal dialysis
- physical activity
- atrial fibrillation
- acute heart failure
- cardiac resynchronization therapy
- patient reported outcomes
- double blind
- patient reported