Login / Signup

Characterization of Arcobacter strains isolated from human stool samples: results from the prospective German prevalence study Arcopath.

Vanessa BrücknerUlrike FiebigerRalf IgnatiusJohannes FriesenMartin EisenblätterMarlies HöckThomas AlterStefan BereswillMarkus M HeimesaatGreta Gölz
Published in: Gut pathogens (2020)
Our study provides evidence for the abundance of putative virulence genes in Arcobacter isolates and prominent cytotoxic effects of A. butzleri and A. lanthieri in vitro. The presence of cdtA, cdtB, cdtC in A. lanthieri points towards CDT secretion as potential mechanism underlying cytotoxicity as opposed to A. butzleri. However, the association of the Arcobacter virulence factors detected and human morbidity should be addressed in future studies.
Keyphrases
  • escherichia coli
  • endothelial cells
  • pseudomonas aeruginosa
  • staphylococcus aureus
  • antimicrobial resistance
  • risk factors
  • induced pluripotent stem cells
  • gene expression
  • risk assessment
  • genetic diversity