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Quercetin and kaempferol from saffron petals alleviated hydrogen peroxide-induced oxidative damage in B16 cells.

Yao ZhangYucui GongJiayun HuLe ZhangMaría José BenitoDurbek UsmanovSabir Z NishanbaevXinjie SongLigen ZouYuanfeng Wu
Published in: Journal of the science of food and agriculture (2024)
The content of kaempferol-3-O-sophoroside and quercetin-3-O-sophoroside was higher in saffron petals than in other parts of saffron. The kaempferol and quercetin obtained from saffron petals could enhance the activity of antioxidant enzyme NQO1 and T-AOC in B16 cells. This indicated that saffron petals, as a potential functional food, may prevent diseases caused by oxidative stress. © 2024 Society of Chemical Industry.
Keyphrases
  • hydrogen peroxide
  • oxidative stress
  • diabetic rats
  • nitric oxide
  • dna damage
  • human health
  • high glucose
  • endothelial cells
  • signaling pathway
  • risk assessment
  • drug induced
  • endoplasmic reticulum stress