Hyperdense artery sign, symptomatic infarct swelling and effect of alteplase in acute ischaemic stroke.
Simiao WuGrant MairGeoff CohenZoe MorrisAnders von HeijneNick BradeyLesley CalaAndré PeetersAndrew J FarrallAlessandro AdamiGillian PotterMing LiuRichard I LindleyPeter A G SandercockJoanna Marguerite Wardlawnull nullPublished in: Stroke and vascular neurology (2020)
Although alteplase was associated with increased risk of symptomatic infarct swelling in patients with or without baseline HAS, it was also associated with accelerated clearance of HAS, which in return reduced swelling, providing further mechanistic insights to underpin the benefits of alteplase.