A new derivative of acetylsalicylic acid and carnosine: synthesis, physical and chemical properties, biological activity.
Olga I KulikovaSergey L StvolinskyVasily A MigulinLudmila A AndreevaIgor Yu NagaevOlga M LopachevaKsenia N KulichenkovaAlexander V LopachevIrina E TrubitsinaTatiana N FedorovaPublished in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2020)
SC preserves pharmacologically significant properties of ASA and carnosine while retaining an anti-ulcer activity and resistance to the carnosinase hydrolysis at the same time. These properties are particularly promising for the potential development of new anti-inflammatory and antithrombotic drugs. Graphical abstract .