D-alanine Inhibits Murine Intestinal Inflammation by Suppressing IL-12 and IL-23 Production in Macrophages.
Hikaru HashimotoTomohisa TakagiKohei AsaedaTakeshi YasudaMariko KajiwaraTakeshi SugayaKatsura MizushimaKen InoueKazuhiko UchiyamaKazuhiro KamadaYasuki HigashimuraRyo InoueYuji NaitoYoshito ItohPublished in: Journal of Crohn's & colitis (2024)
Our results suggest that D-alanine prevents dextran sulphate sodium-induced colitis in mice and suppresses IL-12p35 and IL-23p19 production in macrophages.